Pros and Cons of Stem Cell Transplant Research

It is quite likely that we may have come across stem cells and also have heard about stem cell transplantation. But not many of us would have in-depth knowledge about it. However, if we look around the internet, print media and electronic media, there is quite a bit of talk about stem transplant research and other matters related to it. We will get started by understanding the meaning of stem cells from a layman’s point of view and then try and have a look at the pros and cons associated with stem cells. Put in simple words, stem cells are cells that are extremely critical and crucial for developing new organisms. They are also referred to as non-specialized cells. They have the capability of creating new types of specific cells and they include muscle cells, blood cells, brain cells, and tissue cells. Stem cells continue to grow and thrive in our body till we die but they are known to be more active and more potent in the unborn fetus when compared to the adult body. Some types of cells are capable of creating create all other cells in our body. Few stem cells can repair and even replace damaged tissue cells in our bodies. Embryonic stem cells are the ones that are developed from the female egg once it gets fertilized by sperm. The process could take up to five days.

What Is Stem Cell Transplantation?

In a normal human being, stem cells help produce white blood cells, red blood cells and also platelets amongst other essential things. They are mostly produced in the bone marrow. But in some cases, the bone marrow does not produce adequate bone marrow cells or stem cells because of various reasons. It could be because of some autoimmune disease or other man-made reasons. When a person is treated for cancer and other critical diseases, they are put on some very strong and harsh drugs and chemicals. They are also subject to radiation therapy and chemotherapy. All this could lead to rapid and fast destruction of the bone marrow and this could critically impact the production of bone marrow stem cells. In many cases, the bone marrow may completely stop producing the important stem cells and once this happens it could lead to severe problems. This is when stem cell transplant or bone marrow transplant becomes critical and could make the difference between life and death. However, like all interventions, stem cell transplant and bone marrow transplant has its pros and cons.

 Pros of Stem Cell Transplant

  • As mentioned above, it could make the difference between life and death for a patient.
  • It could help give a boost to the production of red blood cells, white blood cells, and platelets and let us not forget that these are extremely critical.
  •  It could help the patient to get back to normal life.

Cons of Stem Cell Transplant

However, on the flip side stem cell transplantation and bone marrow transplantation has risks and problems. The problem of infection and the problem of rejection are perhaps the most obvious and it keeps happening at regular intervals.

How To Choose The Best Contractor For Custom Concrete Work?

Choosing the best contractor when it comes to custom concrete work for your home is very important. The custom work is meant to make your property even more beautiful and aesthetically appealing. So, when it comes to hiring a contractor for this, you have to be very careful. There are some of the factors that you must consider when choosing the best concrete contractor in Oklahoma City OK for your house. This work is mainly essential for the exterior of your house to build your patio, driveways and walkways. Even it can be used for decking up the pool area.

Factors to consider

Before you go ahead and hire a custom concrete work contractor, you have to follow some of the important factors. These are:

  1. Experience: Well, experience is one of the key factors when it comes to custom work of concrete for your house. With proper and great experience, the contractors can help you to find the best design that can be helpful, last long and look amazing at the same time.
  2. Past works: Another useful factor that you should consider is checking their past works. When it comes to choosing the best concrete contractors in Edmond OK for your custom concrete work, you need to check their previous works. This can help you to gain an idea about their works and skills.
  3. Reliability: Of course, reliability is one of the major factors. You need to ensure that the company you are choosing can be relied on. For that, you have to choose a company which is not only credible but also has a good reputation in the market. You can check for the feedbacks and reviews from the people to make sure whether or not it is reliable in nature.
  4. Quality service: When it comes to custom concrete work, you need to ensure that they have all the essential tools and advanced equipment to provide you with the best custom concrete work. You can get the best result with the best technicians and advanced tools.
  5. Price: Of course price is a very important factor to consider. You need to ask for estimation of the work. Though price plays a crucial factor, you cannot choose the price over the quality of the work. You need to understand that the quality of the work is more important and you need to ensure that you are choosing the best quality workmanship at the most affordable price.

Final words

So, this is all about the custom concrete work and finding the best contractor for it. Since it has a huge role to play, you cannot expect to choose any contractor you want and get the best result. If you are really looking for the best result and the best work, then you need to make sure that you are choosing the right contractor. While hiring one, you have to consider all the above mentioned factors as this will help you to choose the best contractor. You also need to check what type of materials the contractor is using for the work.

Contact US:

Sawan Surgical Aesthetics
Address:14609 Remington Way, Oklahoma City, OK
Phone: (405) 755-3975

Tips On Identifying The Right Assisted Living Facility

Aging is a natural biological process, whether we may agree not agree. There could be situations and a point in our aged life where we may not be able to handle safely all our daily tasks without the help of senior care. Unfortunately, most sons and daughters of elderly people are too busy building their own lives and careers and they rarely have time to take care of their elderly parents. Many of them try and keep their parents away from them citing generation gaps and the pressing demands of modern-day living.

Whatever might the reason, there is a need for elderly people to find a safe, comfortable, physically and emotionally enjoyable place where they can spend the rest of their lives in peace and tranquility. While there are many options available, assisted living facilities are becoming extremely important and popular. Whether it is Long Island or other surrounding areas, many of us would have noticed that there is a significant increase in the number of assisted living facilities. With so many options available, we do have our task cut out when it comes to identifying the right assisted living facility. We are happy to share some of the important attributes that we should keep in mind when it comes to identifying these assisted living facilities in  Great Neck.

Why The Need For Such Facilities

Apart from the reasons mentioned above, studies have shown that around 70 percent of individuals who are above the age of 65 years would need some form of long term care. If you take some time and write down the list of things that elderly people would expect, you would be able to find out that there are quite a few tasks where help is needed. While there could be elders who need assistance at almost each and every step, there could be others who might require help only in certain daily activities. The second group of elderly people would like to spend their lives in a good assisted living facility. Here are a few points to be kept in mind when it comes to identifying the right facilities that offer assisted living in Huntington.

Independent Living Facilities For Seniors

 These kinds of facilities are suitable for elderly people. They will help remove the burden and cost associated with owning one’s own home. It will allow the seniors to focus their time, money and effort on the health of the individual rather than focusing on the physical and emotional aspect of it. It also will allow them to make new friends. Hence, this is an important point to be kept in mind when identifying a suitable living facility.

 Skilled Nursing Care

 You should look for facilities that have skilled nursing facilities. These are required for handling complex health issues, especially those pertaining to dementia and other age-related illnesses. There also could be seniors who might require round the clock help for taking their medicines, bathing and also performing their other day to day activities.

 Safety And Security

 Finally, safety and security are of paramount importance when it comes to choosing the right assisted living facility. Safety of location and security in terms of facilities and amenities are important.

Pros And Cons Of Assisted Living

There is no doubt that the decision to move into a housing community for seniors is not easy. Elderly people and senior citizens often have to face many decisions and this includes choosing the place where they want to live. Gone are the days of joint families where sons and daughters and grandchildren were there to take care of the elderly people. Most seniors, therefore, have to consider various options and choose the right place where they can spend the rest of their lives carefully and without too much of a problem. There could be seniors who are not fully dependent but who require round the clock assistance for their daily activities. For such people, choosing a suitable assisted living facility in Huntington could be a good option. Of course, there are quite a few advantages as far as assisted living is concerned, but at the same time, there also are a few drawbacks. Hence, it is important for family members and senior to sit down and discuss the matter honestly and frankly and then take a final decision about their living preferences.

Benefits Of Assisted Living

 One of the big advantages of assisted living is that the elders will be able to get regular assistance in various activities like dressing, eating, and bathing. Further, they also will have the right kind of environment and assistance to cope with changing needs and health situations. The cost of maintaining a home is very high these days and staying in assisted living facilities in Forest Hills will not be a big burden on the pockets of elderly people. They also will have a home-like setting and the best of privacy, safety and security can be expected.

 Though nursing homes are also a good option, in terms of cost there is no doubt that assisted living facilities are always a much better option. Elderly people who are suffering from early stages of dementia and other physical challenges will most certainly have a chance to live a fairly independent and good life. The facility offers on-site medical care, but you will have to be aware that the care is not present round the clock.

 It is the best option for all those elderly people who are fit enough to be away from full-time attention but need some help and assistance with medication, transportation, meals, and other daily activities such as dressing and bathing.

 Downsides

 On the other hand, there are obviously some downsides also as far as assisted living facilities are concerned. For those with specific budgets in mind, assisted living can be a big problem. Some of the best, assisted living facilities come with exorbitant price tags attached to it. Further, not all senior would find it easy to adjust to a group living, at least in the beginning stages. Elderly people suffer from moderate to severe dementia and other medical conditions will not find this to be suitable for their needs. Compared to a nursing home, the facilities and services offered in assisted living facilities in Huntington are ordinary, to say the least.

In view of the above pros and cons, it is the seniors who have to take the right decision based on their specific needs and requirements.

Contact US:

The Amsterdam at Harborside

Address:
300 E Overlook,Port Washington, NY
Phone: 516-472-6636

Cool, Nebulous Ring Found Around Milky Way’s Supermassive Black Hole

Astrophysicists have discovered what appears to be a disk of cool gas wrapped around the supermassive black hole at the center of our galaxy. The findings, made with the Atacama Large Millimeter/submillimeter Array (ALMA), will give new insight into the workings of accretion, a process by which black holes siphon surrounding materials onto their surfaces.

“We were the first to image this elusive disk and study its rotation,” says Lena Murchikova (PhD ’18), an astrophysicist at the Institute for Advanced Study in Princeton, New Jersey, and lead author of a new paper reporting these findings in the June 6 issue of Nature. “We are also probing accretion onto the black hole. This is important because this is our closest supermassive black hole. Even so, we still have no good understanding of how its accretion works. We hope these new ALMA observations will help the black hole give up some of its secrets.”

Murchikova performed a large portion of this research as a part of her Caltech PhD thesis. She was a Dr. David and Barbara Groce Fellow at Caltech, studying under Caltech advisers Sterl Phinney, professor of theoretical astrophysics, and Nick Scoville, Francis L. Moseley Professor of Astronomy, Emeritus.

Through decades of study, astronomers have developed a clearer picture of the chaotic and crowded neighborhood surrounding the supermassive black hole, named Sagittarius A*, at the center of the Milky Way. It is known that this region is brimming with roving stars, interstellar dust clouds, and a large reservoir of both phenomenally hot and comparatively colder gases. Theorists have argued for 48 years that there must be a vast accretion disk hiding within this reservoir that extends a few tenths of a light-year from the black hole’s event horizon, or the region around a black hole where light can no longer escape.

Until now, however, astronomers have only been able to image a tenuous, hot portion of this gas, which forms a roughly spherical cloud around the black hole and shows no obvious signs of rotation. The hot gas, detected with X-ray telescopes, is estimated to be a blistering 10 million degrees Celsius (18 million degrees Fahrenheit).

The contribution of cooler gas to the accretion flow onto the back hole was previously unknown. ALMA, however, was able to image atomic emission from the area around the supermassive black hole at smaller scales than had been observed before, revealing cool, rotating gas at about 10 thousand Kelvins, or 18,000 degrees Fahrenheit. The observed faint radio signals helped the researchers produce the first-ever image of this cooler gas disk, which has a radius of about 1,000 times the distance between Earth and the sun.

“You can think of the hot gas as being shaped like a bowling ball, with the cool disk being like a thick wedding ring inside, lying at the middle,” says Murchikova.

“We are looking forward to future observations, which may confirm the results and reveal a predicted time-dependence of the disk’s emission due to the motion of hot stars around the black hole,” adds Phinney.

The Nature study, titled, “A Cool Accretion Disk around the Galactic Centre Black Hole,” was supported by the National Radio Astronomy Observatory’s (NRAO’s) ALMA Student Observational Research Program, Dr. David and Barbara Groce, NASA via the Einstein Postdoctoral Fellowship, and the Bezos Fellowship at the Institute for Advanced Study. In addition to Murchikova and Phinney, other co-authors include Anna Pancoast of Harvard University and Roger Blandford of Stanford University. Scoville, though not a co-author, was instrumental in helping with the observational proposals and data analysis.

ALMA is a partnership of the European Organization for Astronomical Research in the Southern Hemisphere (ESO), the National Science Foundation (NSF), and the National Institutes of Natural Sciences (NINS) of Japan in cooperation with the Republic of Chile.

Read the full story from NRAO at https://public.nrao.edu/news/2019-alma-ring/.

How a Giant ‘Thermos Bottle’ Will Help in Understanding Antimatter

One of the big questions physicists are trying to answer is what happened to all the antimatter in our universe. The universe was born out of a hot soup of both matter and antimatter particles (for example, the antiparticle to an electron is a positron). But something happened billions of years ago to tip the balance to matter, and antimatter disappeared. In fact, if this had not happened, we humans would not be here: when antimatter and matter particles collide, they transform into pure energy.

To address this mystery, researchers at Caltech are taking part in an ambitious multi-institutional project called the neutron Electric Dipole Moment experiment, or nEDM, funded by the U.S. Department of Energy and the National Science Foundation. The project will culminate in an experiment at the Oak Ridge National Laboratory in Tennessee in about three years. The idea is to look for what is called an electric dipole moment in neutrons—a phenomenon in which the charges within a neutron are such that one side of the neutron is a tad more negative than the other. This distortion, if large enough, could signal a breakdown in a type of symmetry in physics called charge parity, or CP, that is needed to explain the absence of antimatter in the universe.

Caltech is building a crucial part of the experiment—a giant cryovessel, pictured above, as well as magnetic shielding and coils to produce magnetic fields. The experiment inside the cryovessel, which can be thought of as a giant thermos bottle, will be chilled to temperatures as low as just one-half a degree above absolute zero, or 0.5 Kelvin (-459 degrees Fahrenheit). The idea is to spin ultracold neutrons in a magnetic field inside the chamber, in the same way that MRI machines spin protons in our bodies. An electric field would then be applied, and the researchers would look for very tiny changes in the way the neutrons are spinning—an indication of an electric dipole moment. The sensitivity of the nEDM experiment is equivalent to measuring a distortion in Earth’s diameter of less than one one-hundredth the thickness of a human hair.

The Caltech team expects to deliver the cryovessel, with its magnetic shielding and magnetic field coils, to Oak Ridge in about a year and a half.

Kimberly See Wins Beckman Young Investigator Award

Kimberly See, assistant professor of chemistry, is one of 10 people in the country receiving a Beckman Young Investigator Award this year. The awards support research by chemistry and life sciences faculty members who are still early in their careers.

“We’re very excited to welcome these exceptional scientists to the Beckman family, and look forward to seeing their progress over the next few years,” said Anne Hultgren, executive director of the Arnold and Mabel Beckman Foundation, in a press release.

As a recipient of one of the awards, See will receive $600,000 over four years to fund her research, which focuses on new battery technologies.

“I am extremely humbled and honored to receive the Beckman Young Investigator Award,” See says. “Dr. Beckman’s exceptional ability to use fundamental science to solve societal problems inspires the central goal in my lab: to understand and develop new battery chemistry by probing the fundamental mechanisms that govern the electrochemistry. The BYI Award allows us to explore the very exciting new field of divalent solid-state batteries that use abundant, safe, and inexpensive materials.”

The Beckman Young Investigator Awards are presented by the Arnold and Mabel Beckman Foundation. Arnold Beckman began his association with Caltech as a chemistry graduate student in 1923. He later became a professor at the Institute. In 1935, while still at Caltech, he founded Beckman Instruments, a company that sold a pH meter he had invented the year prior. In 1940, he left Caltech to focus on running the company, which developed a line of scientific testing equipment.

Student-led Outreach to Boost Diversity in STEM

Read more: https://magazine.caltech.edu/post/stemonstrators

For more information about Black Scientists & Engineers of Caltech (BSEC/NSBE), Caltech Latino Association of Student in Engineering and Sciences (CLASES), and the Caltech Center for the Diversity (CCD), visit http://diversity.caltech.edu/about/who_we_serve.

Tirrell Elected to American Philosophical Society

David Tirrell, Caltech’s provost and Ross McCollum-William H. Corcoran Professor of Chemistry and Chemical Engineering, has been elected to the American Philosophical Society. The Society, comprised of scholars from a wide variety of academic disciplines, honors “extraordinary accomplishments in all fields.”

Tirrell, who holds the Carl and Shirley Larson Provostial Chair, works across the disciplines of chemistry, biology, and materials science. He focuses on the genetic code and has shown how modifying the molecular machinery of the cell can lead to new approaches to macromolecular design, protein evolution, biological imaging, and proteome-wide analysis of cellular processes. In recognition of his significant contributions in these areas, Tirrell has received numerous accolades from professional societies and universities around the world. He is one of only 19 individuals elected to all three National Academies: Sciences, Engineering, and Medicine.

Tirrell earned a bachelor’s degree in chemistry from MIT and a PhD in polymer science and engineering from the University of Massachusetts. He served as chair of the Division of Chemistry and Chemical Engineering from 1999 to 2009 and as director of Caltech’s Beckman Institute from 2012 until 2018. He was appointed as Caltech’s 10th provost in 2017.

The American Philosophical Society is the oldest learned society in the United States and was founded in 1743 by Benjamin Franklin for the purpose of “promoting useful knowledge.” More information about the society is online here.

Caltech Honors Staff Members for Excellence, Dedication, Service

At the 64th annual Staff Service & Impact Awards ceremony on May 30, Caltech president Thomas F. Rosenbaum presented awards to more than 200 staff members for their years of service and contributions to the Institute.

Employees honored included: one who has served the Institute for 55 years (Keith Matthews); two for 50 years (Jennifer Daniels and Robert Taylor); six for 40 years; 11 for 35 years; 20 for 30 years; 25 for 25 years; 51 for 20 years; 59 for 15 years; and 48 for 10 years.

Julia McCallin, associate vice president for human resources, served as master of ceremonies for the event, which underscored the vital importance of Caltech’s staff members to the accomplishment of the Institute’s scientific mission. Robert Taylor, 50-year honoree and instrument specialist for LIGO, delivered the keynote address.

The event also included the announcement of two awards, one honoring individual achievement and another recognizing the impact of teams making significant contributions to the work of the Institute.

Rose Royal, department assistant in the Facilities Service Center, received the Thomas W. Schmitt Annual Staff Prize, which honors a staff member whose contributions “embody the values and spirit that enable the Institute to achieve excellence in research and education.”

The award recognized her for her work in helping fix workplace problems such as broken heaters and water leaks—triaging complaints and scheduling needed repairs “with a smile and a great attitude every day.”

Caltech Connect Trainers won the Team Impact Award, which recognizes “teams that make significant contributions to the work and mission of the Institute,” and are able to demonstrate work that has impacted and supported its research or education programs.

The Institute honored the team, created by Student Wellness Services in 2018 as a depression- and suicide-prevention resource, for its work in training more than 400 members of the Caltech community to help identify and assist students in need of counseling or other resources.